In some cases, non-operative treatment gives very good, short and long term results. Our experts apply modern methods of regeneration of cartilage by using the patient’s own (autologous) blood platelet rich plasma (ACP autologous conditioned plasma or PRP platelet rich plasma).
Plasma enriched with platelets is obtained from your own plasma – the liquid is extremely rich in platelets (thrombocytes). Platelets are blood cells that contain a very high concentration of proteins called growth factors. Growth factors act on stem cell tissue in various stages of development, accelerate their growth and multi-amplified cell population. In this way, growth factors stimulate the repair and healing of tendons, ligaments and cartilage, epithelialization (the process by which cells increased parts to re-cover damage), spontaneous closure of the wound and the creation of new connective tissue. It is very important as growth factors derived from the patient’s own blood, so that use does not cause an autoimmune reaction of the body.
Growth factors that are in suspension such as:
- Platelet-derived growth factor (platelet-derived growth factor)
- Transforming growth factor-beta (transforming growth factor beta)
- Fibroblast growth factors (fibroblast growth factor)
- Slice insulin growth factor – 1 (insulin-like growth factor 1)
- Slice insulin growth factor – 2 (insulin-like growth factor 2)
- Vascular endothelial growth factor (vascular endothelial growth factor)
- Epidermal growth factor (epidermal growth factor)
- Interleukin-8 (interleukin 8)
- Keratinocyte growth factor (keratinocyte growth factor)
- Connective tissue growth factor (connective tissue growth factor)
The growth factors for facet syndrome
This method is used in the treatment of chronic degenerative changes in tendons (Achilles tendon, “tennis elbow”, “golfer’s elbow” syndromes involving overloading), followed by acutely injured ligaments, muscles, as well as in case of the need to regenerate damaged cartilage. Indications for treatment with growth factors are chondromalacia and first and second degree, conditional and third degree – in case of changes in large and small joints of the extremities, small joints of the spine, cartilage injuries as a result of trauma and postoperative conditions after the intervention on the cartilage (especially transplantation of cartilage, drilling and mosaic-plastic).
Particularly interesting is the possibility of application of PRP in the treatment of osteoarthritis. In neurosurgery, platelet-enriched plasma is applied to inflamed nerve roots of the cervical and lumbar spine. The last few years this method was used in reconstructive procedures on cartilage and bones, mostly in osteoarthritis, avascular necrosis of bone and rheumatoid arthritis.
The most common indications for the treatment of active and professional athletes are:
- Rupturing of muscle ruptured muscles of the rotator cuff;
- The need for rapid postoperative healing;
- Healing of chronic wounds;
- Chronic inflammation mišićnotetivog appliances;
- Painful feet;
- Nerve damage;
- Acute painful condition of the skeleton unknown etiologije;
- “Facet” syndrome;
- Painful neck;
- Aesthetic orthopedics;
- Acceleration of fracture healing and bone related integration;
- Articular problems.
The use of platelet rich plasma
Platelet-Rich Plasma (PRP) was given at intervals of 4 to 7 days, 4 to 6 times – as indicated by the surgeon, depending on the pathological substrate. In each application, immediately before application, blood is removed from a vein, and then is processed and applied, that is, in the region with ailments. Application own platelet rich plasma in the field of orthopedics and traumatology is the latest form of treatment in our country and has yet to be developed. Using our knowledge and experience gained in this field abroad, we believe that the introduction of this procedure in everyday clinical practice will contribute to the development of science and higher quality treatment of patients in our country. This will show our institution and country of to the world in the best possible manner and opens the door for even more complex research in the fields of orthopedics and traumatology, as well as other specialties.